residue, a modification known to be recognized by a specific E3 enzyme, which directs the ubiquitylation of the protein for rapid degradation. Does this mean that all of these proteins are actively degraded at any given time?
a. Yes; this high turnover rate ensures that their activity is under tight control.
b. Yes; but they are not fully degraded in this way and can still function as protein fragments.
c. No; the destruction signal can be buried in the interior of the protein or bound to other proteins.
d. No; the E3 enzyme recognizing this mark is inactive most of the time.
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